Andreessen Horowitz
VC FundsLeading venture capital firm investing in AI, blockchain, and transformative technology companies.

Andreessen Horowitz company profile
Overview
Andreessen Horowitz, commonly known as a16z, stands as one of the most influential venture capital firms in Silicon Valley, with a particular focus on artificial intelligence investments. Founded in 2009 by Marc Andreessen and Ben Horowitz, the firm has consistently been at the forefront of identifying and nurturing the next generation of transformative technology companies.
The firm’s approach to AI investment is comprehensive, spanning from foundational infrastructure to consumer applications. With over $35 billion in assets under management, a16z has positioned itself as a key catalyst in the AI revolution, backing companies that are reshaping industries from healthcare to finance to creative tools.
Investment Philosophy
Software Is Eating the World
Marc Andreessen’s famous thesis “Software is eating the world” has evolved into “AI is eating software.” The firm believes that artificial intelligence represents the next fundamental platform shift, similar to the internet and mobile revolutions.
Full-Stack Approach
a16z doesn’t just provide capital—they offer comprehensive support including:
- Technical expertise and due diligence
- Talent recruitment and retention
- Go-to-market strategy and business development
- Regulatory guidance and policy advocacy
- Brand building and media relations
Long-Term Partnership
The firm takes a long-term view on AI development, understanding that breakthrough AI companies often require patient capital and sustained support through multiple technology cycles.
AI Portfolio
a16z has built one of the most impressive AI portfolios in venture capital, with investments spanning the entire AI stack:
Company | Category | Investment Stage | Key Focus |
---|---|---|---|
OpenAI | Foundation Models | Series A-C | General AI and Safety |
Mistral AI | Foundation Models | Series A | Open Source LLMs |
Hugging Face | AI Platform | Series B-C | Model Hub and Tools |
Scale AI | Data Infrastructure | Series A-E | AI Training Data |
Jasper | AI Applications | Series A-B | Content Generation |
Lattice | Enterprise AI | Series B-D | HR and People Analytics |
Harvey | Legal AI | Series A | Legal Document Analysis |
ElevenLabs | Voice AI | Series A | Voice Synthesis |
Foundation Model Investments
The firm has been particularly active in foundation model companies, recognizing early that large language models would become the foundation for countless applications. Their investment in OpenAI’s Series A round in 2019 exemplifies their ability to identify paradigm-shifting opportunities.
Infrastructure and Tools
Beyond applications, a16z invests heavily in the infrastructure that powers AI development, including data platforms, MLOps tools, and developer frameworks.
Leadership
Technical Expertise
The firm has assembled a team with deep technical backgrounds in AI and machine learning:
Vijay Pande leads the firm’s AI and bio investments, bringing decades of experience from Stanford University where he pioneered distributed computing for scientific research.
Frank Chen focuses on AI infrastructure and developer tools, with a background in enterprise software and data platforms.
Industry Connections
The partners’ extensive networks in both academia and industry provide portfolio companies with unique access to talent, customers, and strategic partnerships.
Market Impact
Market Making
a16z doesn’t just follow trends—they help create them. Their investments and thought leadership have helped shape the current AI landscape:
- Early recognition of the potential for large language models
- Advocacy for open-source AI development
- Support for AI safety and responsible development practices
Policy Influence
The firm actively engages in AI policy discussions, advocating for regulatory approaches that foster innovation while addressing legitimate safety concerns.
Talent Development
Through their network and platform, a16z helps cultivate the next generation of AI entrepreneurs and technical leaders.
Ecosystem Building
The firm’s approach extends beyond individual companies to building entire ecosystems. Their AI portfolio companies often collaborate and integrate with each other, creating network effects that benefit the entire portfolio.
Investment Criteria
When evaluating AI companies, a16z looks for:
Technical Moats
Companies with unique technical advantages that are difficult to replicate, such as proprietary data, novel architectures, or specialized domain expertise.
Market Timing
Opportunities where technological capabilities are converging with market readiness and regulatory environment.
Exceptional Teams
Founding teams that combine deep technical expertise with strong business acumen and vision.
Scalable Business Models
Companies with clear paths to significant revenue and market impact.
The firm’s combination of capital, expertise, and network effects continues to make it one of the most sought-after investors in the AI space, helping to shape the future of artificial intelligence across industries.